Yes, you can use the gamepad to navigate some parts of the interface, although the dedicated remote control should remain your main option for the best experience.
How to Navigate: Use the Directional Pad (D-pad) - the cross-shaped control located just beneath the left analogue stick on your gamepad - to move up, down, left, and right across the screens.
Where it Works: This navigation is typically supported within the TV Guide and across the interface and within some applications.
Best Practice: For voice search, text entry, or controlling volume and power, the dedicated puck remote control should be your primary tool.